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カタログ番号 | 製品名 | 別名 | ターゲット |
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T16479 | PF-04937319 | Others , Glucokinase | |
PF-04937319 is an activator of glucokinase (EC50 =154.4 μM). PF-04937319 maintains glucose-lowering efficacy while mitigating the risk of hypoglycemia observed with many other glucokinase activators. PF-04937319 can be ... | |||
TQ0055 | AMG-3969 | Glucokinase | |
AMG-3969 is an effective glucokinase-glucokinase regulatory protein interaction (GK-GKRP) disruptor (IC50: 4 nM). | |||
T3312 | AM-2394 | AM2394 | Glucokinase |
AM-2394 is an effective and specific Glucokinase agonist (GKA, EC50: 60 nM), which catalyzes the phosphorylation of glucose to glucose-6-phosphate. AM-2394(AM2394) increases the affinity of GK for glucose by approximatel... | |||
T3104 | Globalagliatin | LY2608204 | Glucokinase |
Globalagliatin (LY2608204) has been used in trials studying the treatment of Diabetes Mellitus, Type 2. | |||
T26712 | AZD-1656 | AZD 1656 | Glucokinase |
AZD-1656 is a glucokinase activator (GKA) that can cause dose-limiting hypoglycemia in normal animals used in embryofetal development studies and type 2 diabetes. | |||
T15159 | Dorzagliatin | HMS5552 | Glucokinase |
Dorzagliatin (HMS5552) is a dual-acting glucokinase (GK) activator. It also improves glycaemic control and pancreatic β-cell function in type 2 diabetes. | |||
T12056 | MK-0941 free base | Glucokinase | |
MK-0941 free base is an orally active glucokinase activator, exhibiting strong glucose-lowering activity and is a potential therapeutic agent for treatment of type 2 diabetes. | |||
T72092 | 2-Deoxy-D-glucose 6-phosphate disodium | ||
2-Deoxy-D-glucose 6-phosphate disodium, a derivative of glucose analog 2-Deoxy-D-glucose, is synthesized in mammalian cells through hexokinase activity on 2-DG. It functions as a competitive inhibitor of glucose metaboli... | |||
T35683 | 2-deoxy-D-Glucose-13C6 | 2-deoxy-D-Glucose-13C6 | |
2-deoxy-D-Glucose-13C6is intended for use as an internal standard for the quantification of 2-deoxy-D-glucose by GC- or LC-MS. 2-deoxy-D-Glucose is a glucose antimetabolite and an inhibitor of glycolysis.1,2It inhibits h... |
カタログ番号 | 製品名 | 別名 | ターゲット |
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T19500 | Palmitelaidic Acid | trans-Palmitoleic acid,9-trans-Hexadecenoic acid | Glucokinase , AMPK , PPAR |
Palmitelaidic Acid (trans-Palmitoleic acid) is one of the most abundant fatty acids in serum and tissue. | |||
T6742 | 2-Deoxy-D-glucose | 2-Deoxy-D-arabino-hexose,2-deoxyglucose,D-Arabino-2-deoxyhexose,Ba 2758,NSC 15193,2-DG | Apoptosis , Hexokinase , HSV |
2-Deoxy-D-glucose (2-DG) is an analog of glucose, an inhibitor of glycolysis. 2-Deoxy-D-glucose has antiviral activity, as well as inhibitory cell proliferation and apoptosis-inducing activity. | |||
T5113 | L-GLUCOSE | L-(-)-Glucose | Others |
L-Glucose (L-(-)-Glucose) is an enantiomer of D-glucose. L-Glucose is not bioavailable to cells as an energy source because it cannot be phosphorylated by hexokinase. | |||
T4726 | D-Glucose 6-phosphate sodium | G6P sodium salt,D-Glucose 6-phosphate sodium salt,Sodium Glucose-6-Phosphate | Others , Endogenous Metabolite |
In cells, D-Glucose 6-phosphate sodium (G6P) is generated when glucose is phosphorylated by hexokinase or glucokinase or by the conversion of glucose-1-phosphate by phosphoglucomutase during glycogenolysis. G6P lies at t... | |||
T5069 | D-Glucose 6-phosphate potassium salt | Others | |
In cells, D-Glucose 6-phosphate potassium salt (G6P) is generated when glucose is phosphorylated by hexokinase or glucokinase or by the conversion of glucose-1-phosphate by phosphoglucomutase during glycogenolysis. G6P l... |